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pCBRG-GRE

CBV20033

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Introduction
Description: pGRE-Luc is designed for monitoring the induction of glucocorticoid response element.The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.When glucocorticoids bind to GR, its primary mechanism of action is the regulation of gene transcription.The unbound receptor resides in the cytosol of the cell. After the receptor is bound to glucocorticoid, the receptor-glucocorticoid complex can take either of two paths.
Plasmid profile:
Unit Size: 1-4μg
Pathway (Activitor): Glucocorticoid Receptor
Pathway profile:
Full Name: NR3C1 (GR)
Cis response element: GRE(glucocorticoid response element)
Shelf Life: One year from date of receipt under proper storage conditions.
Storage: -20°C
Mode of transportation: Ice bag transport
Matters needing attention: For your health, please wear lab clothes and disposable gloves.

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